Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991741 | 1.00 | NAPRT (0.50) | NAPRTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10502087 | 0.82 | NAPRT (0.43) | NAPRTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10502094 | 0.82 | NAPRT (0.43) | NAPRTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL25324982 | 0.81 | CES2 (0.56) | NAPRTALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL9331128 | 0.81 | CES2 (0.56) | NAPRTALDH1A1LMNAMAPTNPSR1 | |
| Methane SCHEMBL9572458 | 0.79 | CES2 (0.54) | NAPRTALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL6998034 | 0.78 | NAPRT (0.64) | NAPRTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10501561 | 0.78 | CES2 (0.43) | NAPRTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7989661 | 0.78 | ALDH1A1 (0.56) | KMT2AALDH1A1LMNAMAPTCYP1A2 | |
| SCHEMBL10501556 | 0.78 | CES2 (0.43) | NAPRTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |