Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991861 | 1.00 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| Hydrochloric Acid SCHEMBL7991906 | 0.99 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| Hydrochloric Acid SCHEMBL7995684 | 0.99 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| SCHEMBL7991774 | 0.85 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| Hydrochloric Acid SCHEMBL7995534 | 0.84 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| SCHEMBL7988684 | 0.81 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| SCHEMBL7977922 | 0.79 | ALDH1A1 (0.42) | POLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL7995274 | 0.79 | ALDH1A1 (0.42) | POLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL7992103 | 0.78 | GPR84 (0.43) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7992097 | 0.78 | GPR84 (0.43) | MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |