SCHEMBL7991774

SCHEMBL7991774

Cc1ccc(-c2[nH]c(CCc3ccccc3)nc2C(=O)Nc2nccs2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.52
POLB P06746 1/20 0.52
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.52
GAA P10253 2/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7995534 0.99 RAB9A (0.51) RAB9APOLBTSHRMAPK1GAA
SCHEMBL7991861 0.85 RAB9A (0.48) RAB9APOLBTSHRMAPK1GAA
SCHEMBL7991789 0.85 RAB9A (0.48) RAB9APOLBTSHRMAPK1GAA
Hydrochloric Acid SCHEMBL7991906 0.84 RAB9A (0.47) RAB9APOLBTSHRMAPK1GAA
Hydrochloric Acid SCHEMBL7995684 0.84 RAB9A (0.47) RAB9APOLBTSHRMAPK1GAA
Hydrochloric Acid SCHEMBL7977438 0.82 MEN1 (0.53) RAB9APOLBTSHRMAPK1GAA
SCHEMBL7988684 0.81 RAB9A (0.59) RAB9APOLBTSHRMAPK1GAA
SCHEMBL7989548 0.81 MEN1 (0.55) RAB9APOLBTSHRMAPK1GAA
SCHEMBL7995385 0.79 MMP2 (0.51) POLBTSHRSMN1; SMN2L3MBTL1KDM4E
SCHEMBL7992155 0.79 RNASEH1 (0.56) RAB9APOLBTSHRGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288061-B1 INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS WELFIDE CORPORATION (JP) 2001-09-11 US disclosed