Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995274 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EPKMHPGDNPSR1 | |
| SCHEMBL7992103 | 0.86 | GPR84 (0.43) | ALDH1A1KMT2AGPR84 | |
| SCHEMBL7992097 | 0.86 | GPR84 (0.43) | ALDH1A1KMT2AGPR84 | |
| SCHEMBL7995385 | 0.81 | MMP2 (0.51) | ALDH1A1KDM4EPKMHPGDNPSR1 | |
| SCHEMBL7991789 | 0.79 | RAB9A (0.48) | ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL7991861 | 0.79 | RAB9A (0.48) | ALDH1A1KDM4EPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7991906 | 0.78 | RAB9A (0.47) | ALDH1A1KDM4EPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7995684 | 0.78 | RAB9A (0.47) | ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL7995185 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EPKMHPGDNPSR1 | |
| SCHEMBL7989981 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4EPKMHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |