Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.82 |
| ▸ | DRD3 | P35462 | 8/20 | 0.82 |
| ▸ | HTR1A | P08908 | 8/20 | 0.82 |
| ▸ | HTR2A | P28223 | 7/20 | 0.82 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.82 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.82 |
| ▸ | DRD1 | P21728 | 3/20 | 0.82 |
| ▸ | DRD5 | P21918 | 3/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | HRH1 | P35367 | 4/20 | 0.74 |
| ▸ | HTR2C | P28335 | 3/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.63 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23861608 | 0.90 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| SCHEMBL6031666 | 0.86 | MAPT (1.00) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| Bromide SCHEMBL6030792 | 0.84 | MAPT (0.97) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| SCHEMBL8544265 | 0.84 | HTR1A (0.78) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| SCHEMBL7977889 | 0.84 | HTR1A (0.78) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL9515562 | 0.84 | MAPT (0.65) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| SCHEMBL7991490 | 0.81 | SIGMAR1 (0.69) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| SCHEMBL2767261 | 0.81 | SIGMAR1 (0.56) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| SCHEMBL10900735 | 0.80 | ADRA1D (0.59) | DRD2DRD3HTR1AHTR2ASIGMAR1 | |
| SCHEMBL10902081 | 0.80 | SIGMAR1 (0.65) | DRD2DRD3HTR1AHTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313297-B1 | CATALYTIC ALKYLATION; BY-PRODUCT INHIBITION | AVENTIS RESEARCH & TECHNOLOGIES (DE) | 2001-11-06 | — | — | US | disclosed |