SCHEMBL799220

SCHEMBL799220

FC(F)(F)C(F)(CC1CO1)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24388689 0.87 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL504498 0.78 ALDH1A1 (0.35) ALDH1A1TDP1TSHRMAPK1
SCHEMBL2848926 0.78 ALDH1A1 (0.35) ALDH1A1TDP1TSHRMAPK1
SCHEMBL1464289 0.78 ALDH1A1 (0.35) ALDH1A1TDP1TSHRMAPK1
SCHEMBL1463184 0.77 TSHR (0.31) ALDH1A1TDP1TSHRMAPK1
SCHEMBL711102 0.77 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL13970924 0.77 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL154145 0.77
SCHEMBL7772709 0.77 ALDH1A1 (0.38) ALDH1A1TDP1TSHRMAPK1
SCHEMBL760371 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814498-B2 Polylactone foams and methods of making the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814498-B2 Polylactone foams and methods of making the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11710854-B2 Functional epoxides in catalyst-based electrolyte compositions for Li-ion batteries ENEVATE CORPORATION (US) 2023-07-25 US disclosed
US-11710854-B2 Functional epoxides in catalyst-based electrolyte compositions for Li-ion batteries ENEVATE CORPORATION (US) 2023-07-25 US disclosed
WO-2022093797-A1 FUNCTIONAL EPOXIDES IN CATALYST-BASED ELECTROLYTE COMPOSITIONS FOR LI-ION BATTERIES ENEVATE CORPORATION (US) 2022-05-05 WO disclosed
US-20220140392-A1 FUNCTIONAL EPOXIDES IN CATALYST-BASED ELECTROLYTE COMPOSITIONS FOR LI-ION BATTERIES ENEVATE CORPORATION 2022-05-05 US disclosed
US-20210324168-A1 POLYLACTONE FOAMS AND METHODS OF MAKING THE SAME NOVOMER, INC. 2021-10-21 US disclosed
US-20210277028-A1 METAL-ORGANIC FRAMEWORK CATALYSTS, AND USES THEREOF NOVOMER, INC. 2021-09-09 US disclosed
US-20070213524-A1 Low pressure carbonylation of heterocycles CORNELL RESEARCH FOUNDATION, INC. (US) 2007-09-13 US disclosed
US-20070213524-A1 Low pressure carbonylation of heterocycles CORNELL RESEARCH FOUNDATION, INC. (US) 2007-09-13 US disclosed
US-20070161537-A1 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams and foam stabilizers GREAT LAKES CHEMICAL CORPORATION (US) 2007-07-12 US disclosed
US-20070149437-A1 Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foams stabilizers E. I. DU PONT DE NEMOURS AND COMPANY 2007-06-28 US disclosed
WO-2007016359-A2 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS GREAT LAKES CHEMICAL CORPORATION (US) 2007-02-08 WO disclosed
WO-2007016359-A2 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS GREAT LAKES CHEMICAL CORPORATION (US) 2007-02-08 WO disclosed
US-20060014918-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY (US) 2006-01-19 US disclosed
EP-0863128-B1 FLUORINATED POLYFUNCTIONAL (METH)ACRYLATE ESTERS, COMPOSITIONS, LOW-REFRACTION MATERIALS, AND ANTIREFLECTION FILMS NOF CORP (JP) 2001-11-21 EP disclosed
US-6087010-A PROVIDES COMPOUNDS HAVING SUFFICIENTLY LOW REFRACTIVE INDEX, SUFFICIENTLY HIGH SURFACE HARDNESS, AND ADHESION NOF CORPORATION (JP) 2000-07-11 US disclosed
EP-0863128-A1 FLUORINATED POLYFUNCTIONAL (METH)ACRYLATE ESTERS, COMPOSITIONS, LOW-REFRACTION MATERIALS, AND ANTIREFLECTION FILMS NOF CORPORATION (JP) 1998-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213524-A1 Low pressure carbonylation of heterocycles CBR1, CYCS, PTGIS ALDH1A1 950/4885TDP1 3713/4885TSHR 4867/4885
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same IDH1, IDH2, IDH3A ALDH1A1 360/4885TDP1 4012/4885TSHR 4868/4885
US-20210277028-A1 METAL-ORGANIC FRAMEWORK CATALYSTS, AND USES THEREOF PPOX, PCCA, MCCC2 ALDH1A1 740/4885TDP1 4722/4885TSHR 4732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.