Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000762 | 0.88 | MME (0.39) | KLK7KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7992235 | 0.80 | LMNA (0.46) | KMT2AL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL1891585 | 0.66 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2MEN1MAPTTP53 | |
| SCHEMBL12125178 | 0.66 | KMT2A (0.69) | KLK7KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL26503455 | 0.65 | ANPEP (0.62) | KLK7KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| Benzene SCHEMBL7286330 | 0.63 | L3MBTL1 (0.58) | KLK7KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2608943 | 0.63 | HTT (0.70) | KLK7KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL147291 | 0.61 | HTT (0.73) | KLK7KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL31185236 | 0.61 | HTT (0.68) | KLK7KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5546903 | 0.61 | PDK1 (0.71) | KMT2ASMN1; SMN2L3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |