Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984698 | 0.95 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL7974240 | 0.86 | RAB9A (0.47) | SMN1; SMN2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL7987763 | 0.83 | RAB9A (0.44) | SMN1; SMN2KMT2AMEN1TDP1SIRT2 | |
| SCHEMBL7991521 | 0.83 | ADORA3 (0.47) | SMN1; SMN2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL7987988 | 0.81 | GAA (0.47) | SMN1; SMN2LMNAGAAKMT2AMEN1 | |
| SCHEMBL7987920 | 0.81 | TP53 (0.47) | SMN1; SMN2KDM4ELMNAGAAKMT2A | |
| SCHEMBL7987851 | 0.79 | LMNA (0.46) | SMN1; SMN2LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL7988637 | 0.79 | NPC1 (0.51) | SMN1; SMN2KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL7991269 | 0.77 | TP53 (0.46) | SMN1; SMN2KDM4ELMNAGAAKMT2A | |
| SCHEMBL7987837 | 0.75 | RECQL (0.47) | SMN1; SMN2KDM4ELMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |