Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386406 | 0.73 | HSD17B10 (0.45) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7990994 | 0.73 | HTR2A (0.52) | ALDH1A1HPGDKDM4ERAB9ALMNA | |
| SCHEMBL7989734 | 0.73 | HTR1A (0.50) | HTR1A | |
| SCHEMBL7447432 | 0.72 | HSD17B10 (0.47) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL7993007 | 0.71 | KDM4E (0.45) | ALDH1A1KDM4EHTR1A | |
| SCHEMBL11785850 | 0.71 | HTR2A (0.59) | ALDH1A1HPGDKDM4ELMNAHTR1A | |
| SCHEMBL7992869 | 0.71 | HTR3A (0.38) | ALDH1A1KDM4ELMNANR4A2 | |
| SCHEMBL5381026 | 0.70 | AR (0.44) | ALDH1A1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL11847909 | 0.70 | HTR2A (0.57) | ALDH1A1HPGDKDM4ELMNAHTR1A | |
| SCHEMBL21256026 | 0.70 | HTR3A (0.58) | ALDH1A1KDM4EHTR1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070728-A1 | 2-[NITROGEN-HETEROCYCLIC]PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |