Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.50 |
| ▸ | HTR1D | P28221 | 7/20 | 0.50 |
| ▸ | HTR1B | P28222 | 7/20 | 0.50 |
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992680 | 0.73 | ALDH1A1 (0.42) | HTR1A | |
| SCHEMBL7978276 | 0.72 | HRH4 (0.49) | HTR1AHTR1DHTR1BSLC6A4 | |
| SCHEMBL7996467 | 0.71 | CDC7 (0.38) | — | |
| SCHEMBL5386406 | 0.70 | HSD17B10 (0.45) | — | |
| SCHEMBL7992869 | 0.70 | HTR3A (0.38) | — | |
| SCHEMBL7978699 | 0.69 | MAPT (0.52) | — | |
| SCHEMBL7447432 | 0.69 | HSD17B10 (0.47) | — | |
| SCHEMBL7990353 | 0.69 | KDM4E (0.52) | HTR1ASLC6A4 | |
| SCHEMBL7989788 | 0.68 | ALDH1A1 (0.58) | — | |
| SCHEMBL5381026 | 0.68 | AR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070728-A1 | 2-[NITROGEN-HETEROCYCLIC]PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |