Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386406 | 0.76 | HSD17B10 (0.45) | ALDH1A1MAPK1KDM4ECDK5CDC7 | |
| SCHEMBL7978276 | 0.76 | HRH4 (0.49) | — | |
| SCHEMBL7978699 | 0.75 | MAPT (0.52) | ALDH1A1TSHRMAPK1LMNAKDM4E | |
| SCHEMBL7447432 | 0.75 | HSD17B10 (0.47) | ALDH1A1TSHRMAPK1KDM4ECDK5 | |
| SCHEMBL7989788 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1LMNAKDM4E | |
| SCHEMBL5381026 | 0.73 | AR (0.44) | ALDH1A1TSHRLMNACDC7GSK3B | |
| SCHEMBL7990353 | 0.72 | KDM4E (0.52) | HTR3AALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL7996467 | 0.72 | CDC7 (0.38) | MGLLMAPK1CDK5CDK5R1TNKS | |
| SCHEMBL7978711 | 0.72 | POLB (0.46) | ALDH1A1TSHRLMNAKDM4EGSK3B | |
| SCHEMBL7992680 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNAKDM4ENR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070728-A1 | 2-[NITROGEN-HETEROCYCLIC]PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |