Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386406 | 0.77 | HSD17B10 (0.45) | CDC7PKN2CDK9CDK5PKN1 | |
| SCHEMBL7447432 | 0.76 | HSD17B10 (0.47) | CDC7PKN2CDK9CDK5PKN1 | |
| SCHEMBL5381026 | 0.74 | AR (0.44) | CDC7CDK2GSK3B | |
| SCHEMBL7978699 | 0.73 | MAPT (0.52) | CDC7MAPK1 | |
| SCHEMBL7992869 | 0.72 | HTR3A (0.38) | CDC7CDK5MAPK1GSK3BPRKCQ | |
| SCHEMBL7989788 | 0.72 | ALDH1A1 (0.58) | MAPK1TNKS2TNKSPARP10PARP2 | |
| SCHEMBL7990353 | 0.71 | KDM4E (0.52) | MAPK1 | |
| SCHEMBL7978522 | 0.71 | — | — | |
| SCHEMBL7989638 | 0.71 | F10 (0.38) | CDC7PKN2CDK9CDK5PKN1 | |
| SCHEMBL7989734 | 0.71 | HTR1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070728-A1 | 2-[NITROGEN-HETEROCYCLIC]PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |
| WO-2001070728-A1 | 2-[NITROGEN-HETEROCYCLIC]PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |