SCHEMBL16669554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16669555	1.00	KMT2A (0.41)	KMT2AALDH1A1LMNAHPGDKDM4E
	SCHEMBL7993233	0.84	CES2 (0.50)	KMT2AALDH1A1LMNAKDM4EMEN1
	SCHEMBL27500253	0.78	KMT2A (0.50)	KMT2AALDH1A1LMNAKDM4EMEN1
	SCHEMBL7408465	0.77	KMT2A (0.47)	KMT2AALDH1A1LMNAKDM4EMEN1
	SCHEMBL28239805	0.75	HTR1A (0.50)	KMT2AALDH1A1LMNAKDM4EPTPN2
	SCHEMBL208341	0.73	TSHR (0.53)	KMT2AALDH1A1LMNAKDM4EMEN1
	SCHEMBL16552873	0.72	CES2 (0.53)	KMT2AALDH1A1LMNAHPGDKDM4E
	SCHEMBL22545632	0.69	MEN1 (0.58)	KMT2ALMNAMAPTMEN1SCN1A
	SCHEMBL9180186	0.69	ALDH1A1 (0.40)	ALDH1A1LMNAMAPTPTPN2PTPN1
	SCHEMBL28817109	0.69	SLC6A3 (0.58)	KMT2AALDH1A1LMNAMEN1PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.