Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 12/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398298 | 0.78 | MMP3 (1.00) | MMP3MMP2MMP9 | |
| SCHEMBL7487118 | 0.73 | MMP3 (0.65) | MMP3 | |
| SCHEMBL7386826 | 0.72 | MMP3 (1.00) | MMP3MMP2MMP9 | |
| SCHEMBL7990113 | 0.70 | MMP3 (0.61) | MMP3 | |
| SCHEMBL7990117 | 0.70 | MMP3 (0.61) | MMP3 | |
| SCHEMBL11841026 | 0.70 | MMP3 (0.55) | MMP3 | |
| SCHEMBL7389205 | 0.69 | MMP3 (1.00) | MMP3MMP2MMP9 | |
| SCHEMBL7398557 | 0.67 | MMP3 (1.00) | MMP3 | |
| SCHEMBL7389210 | 0.66 | MMP3 (0.90) | MMP3 | |
| SCHEMBL7990560 | 0.66 | MMP3 (0.79) | MMP3MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | claimed |
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |