Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.79 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398298 | 0.89 | MMP3 (1.00) | MMP3MMP1MMP2MMP7MMP9 | |
| SCHEMBL7993523 | 0.87 | MMP3 (0.70) | MMP3MMP2MMP9MEN1NPC1 | |
| SCHEMBL7990239 | 0.81 | MMP3 (0.78) | MMP3HSD11B1MMP1MMP2MMP7 | |
| SCHEMBL7996733 | 0.77 | MMP3 (0.49) | MMP3CTSDMEN1NPC1ALDH1A1 | |
| SCHEMBL10935027 | 0.77 | ALDH1A1 (0.52) | MMP3METAP2METAP1CTSDMEN1 | |
| SCHEMBL7389205 | 0.76 | MMP3 (1.00) | MMP3MMP1MMP2MMP9MMP13 | |
| SCHEMBL8484523 | 0.76 | IDO1 (0.49) | MMP3CTSDMEN1ALDH1A1RAB9A | |
| SCHEMBL7996699 | 0.73 | MMP3 (0.76) | MMP3MEN1ALDH1A1KMT2A | |
| SCHEMBL4340803 | 0.72 | CNR1 (0.57) | CTSDMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL27777554 | 0.72 | HTR1B (0.59) | MMP3CTSDMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |