Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681578 | 0.89 | ALDH1A1 (0.61) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL8011529 | 0.87 | LMNA (0.62) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL8013977 | 0.87 | ALOX15 (0.61) | KDM4ELMNAPOLBTP53MAPT | |
| Hydrochloric Acid SCHEMBL27505257 | 0.87 | ALDH1A1 (0.59) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL5288304 | 0.86 | MAPT (0.59) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL7285180 | 0.84 | LMNA (0.55) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL8479686 | 0.84 | RAB9A (0.62) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL14405820 | 0.84 | GAA (0.59) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL8625075 | 0.84 | ALDH1A1 (0.59) | KDM4ELMNAPOLBTP53MAPT | |
| SCHEMBL9072965 | 0.83 | KDM4E (0.54) | KDM4ELMNAPOLBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027077-A2 | HYDROXYSULFONYLALKYLENE-, PHOSPHONOALKYLENE- OR DIFLUORO(PHOSPHONONON)METHYL- SUBSTITUTED BENZENE, OR BENZOFURAN DERIVATIVES AS NON-PEPTIDIC CDC25 INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-19 | — | — | WO | disclosed |