SCHEMBL79937

SCHEMBL79937

C=C(C)C(=O)NC(CC)[Si](OCC)(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.40
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29043136 0.87 TGFBR1 (0.38) TGFBR1
SCHEMBL135381 0.84 TGFBR1 (0.41) TGFBR1
SCHEMBL7154902 0.82 KDM4E (0.31) THRB
SCHEMBL308679 0.81 TGFBR1 (0.39) TGFBR1
SCHEMBL514780 0.80 TGFBR1 (0.38) TGFBR1
SCHEMBL4561830 0.80 ALDH1A1 (0.32)
SCHEMBL1517401 0.79 TGFBR1 (0.37) TGFBR1
SCHEMBL10751465 0.79 TGFBR1 (0.37) TGFBR1
SCHEMBL10753309 0.79 TGFBR1 (0.37) TGFBR1
SCHEMBL2145053 0.78 MGAM (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253828-A Repair and reinforcement material for pigment layer of tomb wall painting in humid environment and preparation method and application thereof 兰州大学 2023-06-13 CN claimed
CN-113213781-A Glass fiber direct roving impregnating compound and preparation method and application thereof 巨石集团有限公司 2021-08-06 CN claimed
EP-2268716-A1 FLEXIBLE HARDCOATS AND SUBSTRATES COATED THEREWITH Momentive Performance Materials Inc. (US) 2011-01-05 EP claimed
WO-2009131680-A1 FLEXIBLE HARDCOATS AND SUBSTRATES COATED THEREWITH MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-10-29 WO claimed
US-20090269504-A1 Flexible hardcoats and substrates coated therewith MOMENTIVE PERFORMANCE MATERIALS INC. 2009-10-29 US claimed
US-20260147278-A1 ORGANIC UNDERLAYER AND METHODS FOR EUV DOSE REDUCTION BREWER SCIENCE, INC. (US) 2026-05-28 US disclosed
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2026-02-17 US disclosed
CN-111607089-B Functional polyhydrosilsesquioxane resin compositions, methods of producing the same, and uses thereof 彼博股份有限公司 2023-10-10 CN disclosed
CN-116253828-A Repair and reinforcement material for pigment layer of tomb wall painting in humid environment and preparation method and application thereof 兰州大学 2023-06-13 CN disclosed
CN-114350332-B Bionic and double-hydrophobic high-efficiency water-based drilling fluid 中国石油大学(北京) 2023-01-31 CN disclosed
CN-113667462-B High-efficiency chip carrying agent Al suitable for water-based drilling fluid 2 O 3 /SiO 2 Composite material 中国石油大学(北京) 2022-10-21 CN disclosed
US-20220162391-A1 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2022-05-26 US disclosed
EP-0541511-B1 Siloxan-containing derivatives of polysaccharides and their use in making paper NAT STARCH CHEM INVEST (US) 1997-08-06 EP disclosed
EP-0385396-B1 Organosiloxane-containing polysaccharides NAT STARCH CHEM INVEST (US) 1994-09-07 EP disclosed
EP-0541511-A2 Siloxan-containing derivatives of polysaccharides and their use in making paper National Starch and Chemical Investment Holding Corporation (US) 1993-05-12 EP disclosed
EP-0540506-A2 Organosiloxane-containing polysaccharides National Starch and Chemical Investment Holding Corporation (US) 1993-05-05 EP disclosed
US-5004791-A Glass fiber sizing composition NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1991-04-02 US disclosed
US-4973680-A PAPERMAKING SIZES NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1990-11-27 US disclosed
EP-0385396-A1 Organosiloxane-containing polysaccharides National Starch and Chemical Investment Holding Corporation (US) 1990-09-05 EP disclosed
US-4711943-A IMPROVED OXYGEN PERMEABILITY AND STABILITY SOLA U.S.A. INC. (US) 1987-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260147278-A1 ORGANIC UNDERLAYER AND METHODS FOR EUV DOSE REDUCTION PARG, KCNK9, PRDM9 TGFBR1 2161/4885THRB 3332/4885
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof MACF1, RTF1, ERCC4 TGFBR1 2280/4885THRB 4016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.