Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989029 | 0.82 | ATM (0.39) | KDM4EGAAPOLBALDH1A1ATM | |
| SCHEMBL7988235 | 0.81 | HRH3 (0.40) | ALDH1A1GRK6MAPTMEN1KMT2A | |
| SCHEMBL7990787 | 0.80 | MCL1 (0.48) | KDM4EGAAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL7990907 | 0.77 | CTSK (0.43) | GAAMAPTMEN1KMT2ACTSK | |
| SCHEMBL7991004 | 0.75 | HRH3 (0.42) | POLBALDH1A1GRK6MAPTMEN1 | |
| Oxalic Acid SCHEMBL7994745 | 0.74 | GAA (0.46) | KDM4EGAAPOLBALDH1A1ATM | |
| SCHEMBL4386655 | 0.72 | KDM4E (0.42) | KDM4EGAAPOLBALDH1A1ATM | |
| SCHEMBL12276383 | 0.69 | KDM4E (0.55) | KDM4EGAAPOLBALDH1A1ATM | |
| SCHEMBL5274330 | 0.67 | KDM4E (0.63) | KDM4EGAAPOLBALDH1A1ATM | |
| SCHEMBL11449929 | 0.66 | KIF11 (0.57) | KDM4EGAAPOLBALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |