Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990745 | 0.88 | HRH2 (0.57) | L3MBTL1HRH2HRH1 | |
| SCHEMBL7987565 | 0.88 | L3MBTL1 (0.55) | L3MBTL1NPC1MAPTHRH2HRH1 | |
| SCHEMBL7987723 | 0.87 | HRH2 (0.56) | L3MBTL1HRH2HRH1 | |
| SCHEMBL7977335 | 0.85 | SMN1; SMN2 (0.51) | L3MBTL1NPC1MAPTHRH2HRH1 | |
| SCHEMBL4376187 | 0.82 | L3MBTL1 (0.59) | L3MBTL1MAPTHRH2HRH1HRH3 | |
| SCHEMBL7987591 | 0.81 | HRH3 (0.42) | L3MBTL1MAPTHRH3 | |
| SCHEMBL7987202 | 0.81 | HRH2 (0.48) | L3MBTL1NPC1MAPTHRH2HRH1 | |
| SCHEMBL7987181 | 0.80 | GAA (0.55) | L3MBTL1MAPTHRH3 | |
| SCHEMBL4376108 | 0.79 | NPC1 (0.48) | L3MBTL1NPC1HRH1HRH3 | |
| SCHEMBL4379129 | 0.79 | FFAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |