Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987181 | 0.85 | GAA (0.55) | MAPTL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL7977335 | 0.83 | SMN1; SMN2 (0.51) | HRH2HRH1MAPTL3MBTL1RAB9A | |
| SCHEMBL4386635 | 0.81 | RAB9A (0.48) | MAPTL3MBTL1RAB9AGAANPC1 | |
| SCHEMBL7994845 | 0.81 | L3MBTL1 (0.48) | HRH2HRH1MAPTL3MBTL1NPC1 | |
| SCHEMBL7987565 | 0.81 | L3MBTL1 (0.55) | HRH2HRH1MAPTL3MBTL1NPC1 | |
| SCHEMBL8934857 | 0.80 | HRH3 (0.39) | GAAPPARGPPARA | |
| SCHEMBL4378557 | 0.80 | POLB (0.42) | FFAR1L3MBTL1 | |
| SCHEMBL4376187 | 0.80 | L3MBTL1 (0.59) | HRH2HRH1MAPTL3MBTL1GAA | |
| SCHEMBL7987591 | 0.80 | HRH3 (0.42) | MAPTL3MBTL1 | |
| SCHEMBL7974440 | 0.79 | GAA (0.56) | MAPTL3MBTL1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |