Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23495196 | 0.92 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL7984822 | 0.79 | EPHX2 (0.57) | HDAC3HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL4725502 | 0.77 | HDAC6 (1.00) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9164607 | 0.73 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL23495205 | 0.70 | FDPS (0.40) | TSHRL3MBTL1ALDH1A1LMNAPOLB | |
| SCHEMBL23495301 | 0.69 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL15008840 | 0.67 | ALDH1A1 (0.53) | HDAC3HDAC1HDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL9084932 | 0.67 | TSHR (0.53) | HDAC3HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL7996560 | 0.67 | L3MBTL1 (0.57) | HDAC3HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL7994849 | 0.66 | EPHX2 (0.50) | HDAC3HDAC1HDAC2HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074789-A1 | NEW (1-ADAMANTYLAMINO)PYRIMIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074789-A1 | NEW (1-ADAMANTYLAMINO)PYRIMIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | disclosed |