Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007197 | 0.92 | CCR1 (0.33) | KDM4E | |
| SCHEMBL8004714 | 0.89 | ALOX15 (0.40) | — | |
| SCHEMBL7996364 | 0.88 | ALB (0.36) | — | |
| SCHEMBL8004923 | 0.87 | PYGL (0.37) | — | |
| SCHEMBL8006223 | 0.86 | PYGL (0.39) | — | |
| SCHEMBL7997127 | 0.86 | STAT6 (0.36) | — | |
| SCHEMBL7995568 | 0.80 | DRD2 (0.34) | — | |
| SCHEMBL7996360 | 0.79 | SMYD3 (0.36) | — | |
| SCHEMBL8007063 | 0.79 | TRPV4 (0.42) | — | |
| SCHEMBL8007066 | 0.79 | TRPV4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |