SCHEMBL7995058

SCHEMBL7995058

Cc1cc(N(C)C)oc1CSCCN

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.33
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8004703 0.98 PRMT6 (0.42) PRMT6L3MBTL1
SCHEMBL11285117 0.80 LMNA (0.34)
SCHEMBL10959685 0.78 PRMT6 (0.59) PRMT6BCHEACHE
SCHEMBL11460483 0.75 PRMT6 (0.44) PRMT6L3MBTL1BCHEACHE
SCHEMBL11479765 0.73 PRMT6 (0.42) PRMT6L3MBTL1BCHEACHE
SCHEMBL10957232 0.72 PRMT6 (0.59) PRMT6BCHEACHE
SCHEMBL11460057 0.72 PRMT6 (0.38) PRMT6L3MBTL1
SCHEMBL11468229 0.72 PRMT6 (0.42) PRMT6CYP3A4
SCHEMBL11244950 0.66 PRMT6 (0.41) PRMT6L3MBTL1
SCHEMBL11534752 0.63 APEX1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114605360-B Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力恒远新材料股份有限公司 2023-05-05 CN claimed
CN-114605360-A Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力香料股份有限公司 2022-06-10 CN claimed
EP-0172608-A1 Novel triazine derivative, process for preparing same and pharmaceutical preparations containing same BIOMEASURE, INC. (US) 1986-02-26 EP claimed
CN-114605360-B Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力恒远新材料股份有限公司 2023-05-05 CN disclosed
CN-114605360-B Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力恒远新材料股份有限公司 2023-05-05 CN disclosed
CN-114605360-B Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力恒远新材料股份有限公司 2023-05-05 CN disclosed
CN-114394710-B Method for treating wastewater from production of aminoethyl thioether 河北海力香料股份有限公司 2022-11-22 CN disclosed
CN-114605360-A Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力香料股份有限公司 2022-06-10 CN disclosed
CN-114605360-A Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力香料股份有限公司 2022-06-10 CN disclosed
CN-114605360-A Preparation method of 2- [ [ [5- (dimethylamino) methyl-2-furyl ] methyl ] thio ] ethylamine 河北海力香料股份有限公司 2022-06-10 CN disclosed
CN-114394710-A Method for treating wastewater from production of aminoethyl thioether 河北海力香料股份有限公司 2022-04-26 CN disclosed
WO-2000029400-A2 PROCEDURE FOR SYNTHESIS OF N-[2[[[5- [(DIALKILAMINO) METHYL]-2- FURANYL] METHYL]THYO] ETHYL]-N'- ALKYL-2-NITRO1,1 ALKENEDIAMINES AND THEIR HYDROCHLORIDES DD'ZDRAVLJE'- FARMACEUTSKO-HEMIJSKA INDUSTRIJA D.D. U. MEŠOVITOJ SVOJINI (YU) 2000-05-25 WO disclosed
EP-0069664-B1 AMINOBENZAMIDES, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANOFI S.A. (FR) 1985-04-03 EP disclosed
EP-0060182-B1 THIOALKYL AMIDE OF NICOTINIC ACID 1-OXIDE, ITS SALTS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS SANOFI S.A. (FR) 1985-01-16 EP disclosed
US-4279819-A GASTROINTESTINAL DISORDERS ALLEN & HANBURYS LTD. (GB) 1981-07-21 US disclosed
US-4255440-A ANTIALLERGENS, ANTIULCER AGENTS ALLEN & HANBURYS LIMITED (GB) 1981-03-10 US disclosed
US-4169855-A ANTIHISTAMINES, ANTISECRETORY AGENTS Allen & Hansbury, Limited (GB) 1979-10-02 US disclosed
US-4128658-A HISTAMINE ANTAGONISTS ALLEN & HANBURYS LIMITED (GB) 1978-12-05 US disclosed