Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181005 | 0.86 | TSHR (0.56) | ALDH1A1HTTLMNAHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27539023 | 0.84 | TSHR (0.54) | ALDH1A1HTTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL13198785 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HTTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL6307398 | 0.84 | TSHR (0.54) | ALDH1A1HTTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL909586 | 0.84 | TSHR (0.54) | ALDH1A1HTTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL2842596 | 0.82 | CFTR (0.57) | SLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| Acetonitrile SCHEMBL28159901 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HTTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL11732114 | 0.79 | CYP19A1 (0.61) | ALDH1A1HTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL19951716 | 0.79 | ALDH1A1 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL8910189 | 0.78 | SLC6A3 (0.58) | SLC6A2SLC6A4SLC6A3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| WO-1997041846-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0672652-A1 | Stabilizers for the prevention of polymerization of (meth)acrylic acid and esters thereof | CIBA-GEIGY AG (CH) | 1995-09-20 | — | — | EP | disclosed |