Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440974 | 0.84 | KMT2A (0.50) | KMT2AHDAC8HDAC6HRH4TDP1 | |
| Hydrochloric Acid SCHEMBL8008010 | 0.83 | KMT2A (0.43) | KMT2AHDAC8HDAC6HRH4TDP1 | |
| Hydrochloric Acid SCHEMBL8008012 | 0.83 | CNR1 (0.43) | KMT2AHDAC8HDAC6HRH4CNR1 | |
| SCHEMBL8444031 | 0.80 | KMT2A (0.46) | KMT2AHDAC8HDAC6HRH4TDP1 | |
| SCHEMBL8005356 | 0.77 | MAPT (0.44) | KMT2ATP53SMN1; SMN2 | |
| SCHEMBL8007343 | 0.76 | ALDH1A1 (0.58) | KMT2ACYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL8818855 | 0.75 | CA12 (0.53) | KMT2ATDP1CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8443489 | 0.74 | CYP2D6 (0.45) | KMT2AHDAC8HDAC6CYP2D6CYP2C9 | |
| SCHEMBL7995563 | 0.74 | LMNA (0.61) | KMT2ACYP2D6CYP2C9LMNASMN1; SMN2 | |
| SCHEMBL8007345 | 0.74 | CHRM3 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017917-A | Guanidine derivatives | FUJISAWA PHARAMCEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0876338-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025310-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |