Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007343 | 0.94 | ALDH1A1 (0.58) | LMNACYP2D6CYP2C9ALDH1A1HTR1A | |
| Hydrochloric Acid SCHEMBL8007350 | 0.85 | MEN1 (0.51) | LMNACYP2D6CYP2C9GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8007354 | 0.84 | GAA (0.50) | LMNACYP2D6CYP2C9GAAALDH1A1 | |
| SCHEMBL8007800 | 0.79 | ADORA1 (0.47) | GAAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8007345 | 0.78 | CHRM3 (0.51) | — | |
| SCHEMBL8664616 | 0.78 | MAPK1 (0.47) | LMNACYP2C9ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8440888 | 0.77 | LMNA (0.53) | LMNACYP2D6CYP2C9ALDH1A1HTR1A | |
| SCHEMBL8005080 | 0.77 | KMT2A (0.51) | LMNAALDH1A1MAOBMAPK1SMN1; SMN2 | |
| SCHEMBL7824081 | 0.77 | LMNA (0.67) | LMNACYP2D6CYP2C9GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7995813 | 0.76 | KMT2A (0.50) | LMNAALDH1A1MAPK1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017917-A | Guanidine derivatives | FUJISAWA PHARAMCEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0876338-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025310-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |