Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 15/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8662398 | 0.86 | CHRM3 (0.46) | CHRM3TLR9TLR8TLR7ADORA2B | |
| SCHEMBL8007343 | 0.79 | ALDH1A1 (0.58) | — | |
| SCHEMBL7995563 | 0.78 | LMNA (0.61) | — | |
| SCHEMBL8005080 | 0.77 | KMT2A (0.51) | ADORA1PDE4B | |
| Hydrochloric Acid SCHEMBL7995813 | 0.76 | KMT2A (0.50) | ADORA1PDE4B | |
| SCHEMBL7995581 | 0.75 | MCHR1 (0.46) | — | |
| SCHEMBL8007800 | 0.75 | ADORA1 (0.47) | ADORA1PDE4B | |
| SCHEMBL5622140 | 0.75 | ADORA1 (0.55) | CHRM3CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL7995541 | 0.74 | KMT2A (0.46) | — | |
| SCHEMBL8664616 | 0.74 | MAPK1 (0.47) | ADORA1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017917-A | Guanidine derivatives | FUJISAWA PHARAMCEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0876338-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025310-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |