Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 7/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735113 | 0.84 | GAA (0.43) | MAPTKDM4EHPGDPPARGRXFP1 | |
| SCHEMBL7995977 | 0.83 | ACLY (0.39) | MAPTRXFP1SMN1; SMN2TP53 | |
| SCHEMBL6790398 | 0.81 | GAA (0.50) | MAPTKDM4ERXFP1TP53 | |
| SCHEMBL1599472 | 0.80 | ACLY (0.40) | MAPTSMN1; SMN2 | |
| SCHEMBL5735580 | 0.79 | ACLY (0.39) | MAPTHPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL5736818 | 0.79 | ACLY (0.39) | KDM4EPPARGCETP | |
| SCHEMBL6790401 | 0.78 | ACLY (0.39) | MAPTSMN1; SMN2TP53 | |
| SCHEMBL7994515 | 0.78 | ACLY (0.41) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7993931 | 0.78 | GAA (0.41) | MAPTKDM4EHPGDPPARGRXFP1 | |
| SCHEMBL8001808 | 0.77 | GAA (0.42) | MAPTRXFP1TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |