Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 2/20 | 0.59 |
| ▸ | USP7 | Q93009 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996719 | 0.82 | PTGES (0.64) | USP8USP7MAPTKDM4ERAB9A | |
| SCHEMBL7994928 | 0.75 | PTGES (0.42) | USP8USP7MAPK1MAPTKDM4E | |
| SCHEMBL7996571 | 0.74 | USP8 (0.59) | USP8USP7MAPK1MAPTKDM4E | |
| SCHEMBL1512633 | 0.74 | USP8 (1.00) | USP8USP7MAPK1MAPTKDM4E | |
| SCHEMBL11134106 | 0.70 | MAPT (0.73) | USP8USP7MAPK1MAPTKDM4E | |
| SCHEMBL7984632 | 0.67 | USP8 (0.60) | USP8USP7MAPK1MAPTRAB9A | |
| SCHEMBL23271697 | 0.64 | MAPT (0.64) | USP8USP7MAPK1MAPTKDM4E | |
| SCHEMBL30002993 | 0.64 | MAPT (0.64) | USP8USP7MAPK1MAPTKDM4E | |
| SCHEMBL7994964 | 0.64 | PTGES (0.45) | USP8USP7MAPK1MAPTRAB9A | |
| SCHEMBL7983849 | 0.64 | PTGES (0.57) | USP8MAPK1MAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |