Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP8 | P40818 | 3/20 | 0.42 |
| ▸ | USP7 | Q93009 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998545 | 0.82 | USP8 (0.59) | PTGESALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7984591 | 0.81 | PTGES (0.61) | PTGESALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7984632 | 0.81 | USP8 (0.60) | PTGESALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7984832 | 0.79 | PTGES (0.63) | PTGESMEN1KMT2AMAPTTDP1 | |
| SCHEMBL7994971 | 0.79 | PTGES (0.59) | PTGES | |
| SCHEMBL23876437 | 0.78 | PTGES (1.00) | PTGESALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7983849 | 0.78 | PTGES (0.57) | PTGESALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7996575 | 0.77 | PTGES (0.55) | PTGESMEN1KMT2AMAPTRAB9A | |
| SCHEMBL7996440 | 0.76 | PTGES (0.54) | PTGESALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7984763 | 0.76 | PTGES (0.54) | PTGESALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |