Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 11/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990239 | 0.87 | MMP3 (0.78) | MMP3ALDH1A1KMT2A | |
| SCHEMBL7386826 | 0.86 | MMP3 (1.00) | MMP3ALDH1A1MEN1KMT2A | |
| SCHEMBL1648068 | 0.76 | NCEH1 (0.50) | MMP3NCEH1MEN1KMT2A | |
| SCHEMBL27854517 | 0.74 | NCEH1 (0.52) | MMP3NCEH1MEN1KMT2AMAPT | |
| SCHEMBL7397190 | 0.73 | MMP3 (1.00) | MMP3KMT2A | |
| SCHEMBL7990560 | 0.73 | MMP3 (0.79) | MMP3ALDH1A1MEN1KMT2A | |
| SCHEMBL7398298 | 0.73 | MMP3 (1.00) | MMP3MEN1KMT2A | |
| SCHEMBL27854489 | 0.72 | NCEH1 (0.51) | MMP3NCEH1MEN1KMT2AMAPT | |
| SCHEMBL27876343 | 0.72 | NCEH1 (0.56) | MMP3ALDH1A1NCEH1MEN1KMT2A | |
| SCHEMBL7993523 | 0.70 | MMP3 (0.70) | MMP3ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |