Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 8/20 | 0.78 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386826 | 0.88 | MMP3 (1.00) | MMP3MMP2MMP7MMP14MMP1 | |
| SCHEMBL7996699 | 0.87 | MMP3 (0.76) | MMP3ALDH1A1KMT2A | |
| SCHEMBL7990560 | 0.81 | MMP3 (0.79) | MMP3HSD11B1MMP2MMP7MMP14 | |
| SCHEMBL7993490 | 0.78 | MMP3 (0.78) | MMP3 | |
| SCHEMBL7996980 | 0.77 | MMP3 (0.69) | MMP3 | |
| SCHEMBL1649329 | 0.74 | METAP2 (0.54) | MMP3METAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7398298 | 0.72 | MMP3 (1.00) | MMP3MMP2MMP7MMP14MMP1 | |
| SCHEMBL10580468 | 0.72 | HSD11B1 (0.52) | MMP3HSD11B1MMP2MMP14MMP1 | |
| SCHEMBL7993523 | 0.71 | MMP3 (0.70) | MMP3MMP2MMP9ALDH1A1LMNA | |
| SCHEMBL9317066 | 0.70 | SOX18 (0.51) | METAP2METAP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |