Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990560 | 0.87 | MMP3 (0.79) | MMP3ALDH1A1MMP2MMP9NPC1 | |
| SCHEMBL7993470 | 0.83 | MMP3 (0.47) | MMP3MAPTALOX5ALDH1A1DHODH | |
| SCHEMBL7398298 | 0.82 | MMP3 (1.00) | MMP3MMP2MMP9MEN1KMT2A | |
| SCHEMBL7979043 | 0.74 | MMP3 (0.65) | MMP3MAPTALDH1A1MMP2MMP9 | |
| SCHEMBL7997188 | 0.73 | MMP3 (0.40) | MMP3MAPTTP53NPC1RAB9A | |
| SCHEMBL7994042 | 0.72 | L3MBTL1 (0.50) | MMP3MAPTDHODHNPC1MEN1 | |
| SCHEMBL7990239 | 0.71 | MMP3 (0.78) | MMP3ALDH1A1GAAMMP2MMP9 | |
| SCHEMBL7389205 | 0.71 | MMP3 (1.00) | MMP3GAAMMP2MMP9 | |
| SCHEMBL7996699 | 0.70 | MMP3 (0.76) | MMP3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7392568 | 0.70 | MMP3 (1.00) | MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |