Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330492 | 0.82 | GPR119 (0.36) | GPR119L3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL6160554 | 0.71 | FKBP1A (0.39) | KMT2AADORA3FKBP1AALDH1A1EPHX2 | |
| SCHEMBL6097679 | 0.69 | CCKBR (0.40) | L3MBTL1MEN1KMT2AADORA3FKBP1A | |
| SCHEMBL6330062 | 0.67 | EPHX2 (0.37) | GPR119L3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL6160177 | 0.66 | KMT2A (0.39) | KMT2AADORA3FKBP1AALDH1A1EPHX2 | |
| SCHEMBL6096321 | 0.65 | CCKBR (0.61) | ADORA3FKBP1AEPHX2 | |
| SCHEMBL6159433 | 0.64 | CCKBR (0.47) | ADORA3EPHX2 | |
| SCHEMBL8626667 | 0.64 | SYK (0.48) | CTSLMAPTEPHX2CYP3A4TSHR | |
| SCHEMBL722912 | 0.63 | CNR2 (0.57) | MAPK1POLBTSHR | |
| SCHEMBL6159409 | 0.62 | CCKBR (0.46) | ADORA3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085723-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS (II) | JAMES BLACK FOUNDATION LIMITED (GB) | 2001-11-15 | — | — | WO | disclosed |