Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.42 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387913 | 0.85 | CA1 (0.49) | KMT2AALDH1A1CA12CA1CA2 | |
| SCHEMBL8000580 | 0.84 | SMN1; SMN2 (0.49) | KMT2AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL27167710 | 0.79 | CYP17A1 (0.51) | CA1CA2MMP2MMP9PPARA | |
| SCHEMBL3258334 | 0.79 | CA2 (0.50) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL5755549 | 0.76 | HPGD (0.59) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL8405338 | 0.76 | POLB (0.54) | ALDH1A1 | |
| SCHEMBL12266895 | 0.76 | CYP1A2 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL8866937 | 0.76 | ALDH1A1 (0.56) | KMT2AALDH1A1HRH3SAE1UBA2 | |
| SCHEMBL8047223 | 0.76 | ALDH1A1 (0.56) | KMT2AALDH1A1HRH3SAE1UBA2 | |
| SCHEMBL12678507 | 0.76 | PLK1 (0.58) | KMT2AALDH1A1HRH3SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |