Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.53 |
| ▸ | MMP13 | P45452 | 11/20 | 0.53 |
| ▸ | MMP1 | P03956 | 9/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.51 |
| ▸ | MMP2 | P08253 | 7/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MMP7 | P09237 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932142 | 0.81 | MMP9 (0.51) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7418098 | 0.75 | MMP2 (0.59) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL13813079 | 0.72 | MMP2 (0.47) | MMP9MMP13MMP1MMP2MMP3 | |
| SCHEMBL12674211 | 0.72 | MMP2 (0.47) | MMP9MMP13MMP1MMP2MMP3 | |
| SCHEMBL27512626 | 0.71 | MMP13 (0.75) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7324090 | 0.71 | MMP13 (0.71) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL6934202 | 0.71 | MMP13 (0.53) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL10763538 | 0.70 | MMP2 (0.46) | MMP9MMP13MMP1MMP2MMP3 | |
| SCHEMBL8013573 | 0.70 | MMP2 (0.55) | MMP9MMP13MMP1MMP2MMP3 | |
| SCHEMBL7366507 | 0.70 | MMP2 (0.52) | MMP9MMP13MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |