SCHEMBL7997463

SCHEMBL7997463

Cc1c(CO)cccc1SC(CO)(SCCCl)c1cccc(CCl)c1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7997459 0.73 PDCD1 (0.37) PDCD1CD274
SCHEMBL7975278 0.68 PDCD1 (0.33) PDCD1CD274
SCHEMBL7994038 0.68 HTR7 (0.33)
SCHEMBL7974379 0.63 ALDH1A1 (0.34) PDCD1CD274
SCHEMBL10176579 0.63 PDCD1 (0.50) PDCD1CD274
SCHEMBL16957698 0.63 PDCD1 (0.50) PDCD1CD274
SCHEMBL7994077 0.62 PDCD1 (0.46) PDCD1CD274
SCHEMBL10365374 0.62 APOBEC3G (0.57) PDCD1CD274
SCHEMBL17845893 0.62 P2RX7 (0.42)
SCHEMBL737569 0.62 PDCD1 (0.48) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001034578-A1 COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY ASTRAZENECA AB (SE) 2001-05-17 WO disclosed