Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013271 | 0.91 | CCKBR (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL924672 | 0.75 | MAPK9 (0.49) | MAPK9MAPK10BCL2BCL2L1ALDH1A1 | |
| SCHEMBL13998433 | 0.74 | MAPK9 (0.48) | MAPK9MAPK10BCL2BCL2L1ALDH1A1 | |
| SCHEMBL6542892 | 0.73 | HPGD (0.41) | MAPK9MAPK10SMN1; SMN2KMT2A | |
| SCHEMBL15161568 | 0.72 | L3MBTL1 (0.41) | MAPK9MAPK10BCL2BCL2L1ALDH1A1 | |
| SCHEMBL1518950 | 0.72 | L3MBTL1 (0.47) | BCL2BCL2L1ALDH1A1MEN1KMT2A | |
| SCHEMBL12334071 | 0.72 | RORA (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL12334602 | 0.71 | CCKBR (0.52) | BCL2BCL2L1ALDH1A1MEN1KMT2A | |
| SCHEMBL16502984 | 0.71 | LMNA (0.54) | MAPK9MAPK10BCL2BCL2L1SMN1; SMN2 | |
| SCHEMBL3547639 | 0.71 | BCL2 (0.45) | MAPK9MAPK10BCL2BCL2L1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |