Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734469 | 0.93 | RAB9A (0.43) | RAB9AMEN1KMT2ARIOK2GSK3A | |
| SCHEMBL5736347 | 0.81 | MAPT (0.44) | RAB9AMEN1KMT2ANPC1MAPT | |
| Bromide SCHEMBL8001925 | 0.78 | MAPT (0.42) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL8001928 | 0.77 | MAPT (0.41) | RAB9AMEN1KMT2APSEN1PSEN2 | |
| SCHEMBL7994622 | 0.69 | FFAR2 (0.32) | FFAR2ALDH1A1 | |
| SCHEMBL14629743 | 0.69 | RAB9A (0.59) | RAB9AMEN1KMT2ACA12CA1 | |
| SCHEMBL5741082 | 0.66 | GPR88 (0.55) | RAB9AMEN1KMT2ACA1CA2 | |
| SCHEMBL5734992 | 0.66 | GAA (0.34) | RAB9AMEN1KMT2ANPC1TP53 | |
| SCHEMBL27063852 | 0.66 | SMN1; SMN2 (0.63) | RAB9AMEN1KMT2ACA12CA1 | |
| SCHEMBL7795343 | 0.65 | KLK7 (0.67) | RAB9AMEN1KMT2ANPC1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |