Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.55 |
| ▸ | MMP13 | P45452 | 3/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567555 | 0.83 | MEN1 (0.54) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL7355241 | 0.82 | KDM4E (0.67) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL10340077 | 0.80 | HTR2A (0.76) | OPRM1HTR2A | |
| SCHEMBL7956096 | 0.80 | MMP1 (0.55) | MMP1MMP9MMP13ADAM17MEN1 | |
| SCHEMBL7506962 | 0.79 | MMP1 (0.54) | MMP1MMP9MMP13ADAM17PKM | |
| SCHEMBL18191776 | 0.79 | HTR2A (0.66) | OPRM1HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL9649705 | 0.79 | HTR2A (0.74) | OPRM1HTR2A | |
| Hydrochloric Acid SCHEMBL27696810 | 0.78 | OPRM1 (0.62) | OPRM1HTR2ASIGMAR1 | |
| SCHEMBL7841889 | 0.78 | SIGMAR1 (0.65) | OPRM1SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL1414107 | 0.77 | SIGMAR1 (0.63) | OPRM1SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |