Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999178 | 0.91 | L3MBTL1 (0.33) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8000644 | 0.89 | L3MBTL1 (0.32) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8008226 | 0.88 | PKM (0.32) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8005068 | 0.88 | L3MBTL1 (0.31) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8000613 | 0.82 | L3MBTL1 (0.32) | L3MBTL1KDM4EALDH1A1LMNAADORA3 | |
| SCHEMBL10292801 | 0.79 | ALDH1A1 (0.33) | KDM4EALDH1A1KMT2ASLC6A3 | |
| SCHEMBL10293206 | 0.79 | SLC6A3 (0.33) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10259721 | 0.79 | SLC6A3 (0.33) | MAPTSLC6A3 | |
| SCHEMBL7998466 | 0.78 | PKM (0.36) | KDM4EALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL10293216 | 0.78 | SLC6A3 (0.32) | KDM4EALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134987-A1 | DIFLUOROMETHYL-CONTAINING MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |