SCHEMBL7998744

SCHEMBL7998744

CN(C)CCc1cc[c]s1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 0.39
HRH3 Q9Y5N1 3/20 0.39
HTR2A P28223 3/20 0.35
HTR2C P28335 3/20 0.35
HTR2B P41595 3/20 0.35
HTR1A P08908 1/20 0.33
HTR6 P50406 1/20 0.33
CHRNA7 P36544 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16892560 0.80 HTR1A (0.37) HRH3HTR2AHTR2CHTR1AHTR6
SCHEMBL208397 0.78
SCHEMBL131435 0.76
SCHEMBL2681937 0.71
SCHEMBL735087 0.69 ESR1 (0.38) HTR2AHTR2C
SCHEMBL1286045 0.69 ESR1 (0.38) HTR2AHTR2C
SCHEMBL5457355 0.68 HTR7 (0.41) HTR2AHTR1A
SCHEMBL1631743 0.66
SCHEMBL2376616 0.64 TAAR1 (0.54) TAAR1HTR2AHTR2CHTR2BHTR6
SCHEMBL6990455 0.62 ALDH1A1 (0.46) TAAR1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6107312-A BACTERICIDE BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-08-22 US disclosed