Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947062 | 0.96 | MITF (0.43) | MITFOPRK1HTTPAX8KMT2A | |
| SCHEMBL7946743 | 0.94 | MITF (0.45) | MITFOPRK1HTTPAX8KMT2A | |
| SCHEMBL7951886 | 0.94 | MITF (0.45) | MITFOPRK1HTTPAX8KMT2A | |
| SCHEMBL7993224 | 0.90 | MEN1 (0.42) | MITFOPRK1HTTPAX8KMT2A | |
| SCHEMBL7948016 | 0.87 | POLB (0.38) | MITFOPRK1HTTPAX8KMT2A | |
| SCHEMBL7947094 | 0.86 | POLB (0.37) | MITFOPRK1HTTPAX8KMT2A | |
| SCHEMBL7938360 | 0.85 | POLB (0.36) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL7945107 | 0.84 | POLB (0.36) | ALDH1A1MAPTNPC1RAB9AEPHX2 | |
| SCHEMBL7947164 | 0.84 | PLA2G2A (0.37) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL7951892 | 0.84 | POLB (0.39) | MITFOPRK1HTTPAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |