Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MITF | O75030 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947062 | 0.94 | MITF (0.43) | MEN1KMT2AMITFMAPTALDH1A1 | |
| SCHEMBL7951886 | 0.94 | MITF (0.45) | MEN1KMT2AMITFMAPTALDH1A1 | |
| SCHEMBL7946743 | 0.94 | MITF (0.45) | MEN1KMT2AMITFMAPTALDH1A1 | |
| SCHEMBL7998793 | 0.90 | MITF (0.41) | MEN1KMT2AMITFMAPTALDH1A1 | |
| SCHEMBL7969240 | 0.88 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1NPSR1NPC1 | |
| SCHEMBL7948016 | 0.87 | POLB (0.38) | MEN1KMT2AMITFMAPTALDH1A1 | |
| SCHEMBL7985982 | 0.87 | KMT2A (0.40) | MEN1KMT2AMITFMAPTALDH1A1 | |
| SCHEMBL7947094 | 0.86 | POLB (0.37) | MEN1KMT2AMITFMAPTALDH1A1 | |
| SCHEMBL7938408 | 0.85 | CYP2C9 (0.43) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL7938405 | 0.85 | FKBP1A (0.38) | MEN1KMT2AALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |