Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010715 | 0.90 | CA12 (0.40) | HSD11B1FLT1FLT4KDRMEN1 | |
| SCHEMBL8009035 | 0.89 | HSD11B1 (0.36) | HSD11B1MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL8007957 | 0.88 | ALDH1A1 (0.41) | HSD11B1KMT2AUSP2PTGS2ALDH1A1 | |
| SCHEMBL2744207 | 0.87 | HSD11B1 (0.43) | HSD11B1KMT2AUSP2PTGS2ALDH1A1 | |
| SCHEMBL8014575 | 0.86 | HSD11B1 (0.38) | HSD11B1MEN1KMT2AUSP2PTGS2 | |
| SCHEMBL8011292 | 0.85 | KMT2A (0.41) | HSD11B1MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL8008055 | 0.85 | FLT1 (0.41) | HSD11B1FLT1FLT4KDRMEN1 | |
| SCHEMBL7998786 | 0.84 | HSD11B1 (0.36) | HSD11B1MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL7998848 | 0.80 | HSD11B1 (0.38) | HSD11B1MEN1KMT2AUSP2PTGS2 | |
| SCHEMBL8008194 | 0.79 | FBP1 (0.41) | FLT1FLT4KDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165668-A | N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2000-12-26 | — | — | US | disclosed |