Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659356 | 0.85 | HPGD (0.64) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL9819481 | 0.85 | KMT2A (0.62) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL3793403 | 0.83 | NLRP3 (0.53) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2091197 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KDM4EHTTHPGDPOLB | |
| SCHEMBL513877 | 0.82 | MEN1 (0.57) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL3790475 | 0.82 | PDK1 (0.54) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL2093882 | 0.82 | RAF1 (0.53) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL514178 | 0.82 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL30207788 | 0.82 | PDK1 (0.54) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL1189632 | 0.82 | ALDH1A1 (0.77) | MEN1KMT2AALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699994-A | METHYLATING N-PHENYL CARBAMIC ACID ESTER | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-10-13 | — | — | US | claimed |
| CN-115850119-A | Synthetic method of 2-chloro aromatic amine compound | 南昌大学 | 2023-03-28 | — | — | CN | disclosed |
| EP-3508473-B1 | METHOD FOR PRODUCING CARBAMIC ACID ESTER | AIST (JP) | 2021-05-26 | — | — | EP | disclosed |
| US-10752579-B2 | Production method of carbamic acid ester | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2020-08-25 | — | — | US | disclosed |
| CN-107434774-B | Method for synthesizing diphenylmethane dicarbamic acid ester from phenyl carbamate | 中国石油化工股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| EP-3508473-A1 | METHOD FOR PRODUCING CARBAMIC ACID ESTER | National Institute of Advanced Industrial Science and Technology (JP) | 2019-07-10 | — | — | EP | disclosed |
| US-20190185420-A1 | PRODUCTION METHOD OF CARBAMIC ACID ESTER | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2019-06-20 | — | — | US | disclosed |
| US-20170355997-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-12-14 | — | — | US | disclosed |
| US-9771592-B2 | Methods and compositions for treating or preventing pruritis | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| WO-2014184070-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-20080027095-A1 | Use Of 3-Substituted-2-(Diphenylmethy)-1-Azabicyclo[2.2.2]Octanes For Treating Mrg-X1 Receptor Mediated Diseases | MERCK SHARP & DOHME CORP. | 2008-01-31 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-20050143454-A1 | 4-Alkyl-2-haloaniline derivative and process and process for producing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2005-06-30 | — | — | US | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| EP-1506954-A1 | 4-ALKYL-2-HALOANILINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2005-02-16 | — | — | EP | disclosed |
| US-4699994-A | METHYLATING N-PHENYL CARBAMIC ACID ESTER | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0216273-A2 | Method of manufacturing diphenylmethane dicarbamic acid esters | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0032733-B1 | PROCESS FOR PREPARING POLYMETHYLENE POLYPHENYL POLYCARBAMATES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-06-13 | — | — | EP | disclosed |
| EP-0032733-A1 | Process for preparing polymethylene polyphenyl polycarbamates | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1981-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355997-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | ITCH, CCL11, CPA3 | MEN1 4289/4885KMT2A 4208/4885ALDH1A1 2589/4885 |
| US-20080027095-A1 | Use Of 3-Substituted-2-(Diphenylmethy)-1-Azabicyclo[2.2.2]Octanes For Treating Mrg-X1 Receptor Mediated Diseases | MRGPRX1, MRGPRX2, MRGPRX4 | MEN1 2460/4885KMT2A 940/4885ALDH1A1 2071/4885 |
| US-20050143454-A1 | 4-Alkyl-2-haloaniline derivative and process and process for producing the same | NAT1, CYP4X1, HAX1 | MEN1 1499/4885KMT2A 279/4885ALDH1A1 441/4885 |
| US-20190185420-A1 | PRODUCTION METHOD OF CARBAMIC ACID ESTER | CA2, CA7, CA4 | MEN1 2437/4885KMT2A 243/4885ALDH1A1 3215/4885 |
| US-10752579-B2 | Production method of carbamic acid ester | CA2, CA7, CA4 | MEN1 2437/4885KMT2A 243/4885ALDH1A1 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.