Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002652 | 0.77 | L3MBTL1 (0.43) | MAOBPPARGLMNANFE2L2PTGES2 | |
| SCHEMBL7989475 | 0.77 | NFE2L2 (0.50) | CYP19A1MAOBLMNANFE2L2ALDH1A1 | |
| SCHEMBL7988653 | 0.75 | MAOB (0.41) | MAOAMAOBPPARGLMNANFE2L2 | |
| SCHEMBL8001632 | 0.75 | MAPT (0.48) | MAOAMAOBPPARGLMNANFE2L2 | |
| SCHEMBL8000279 | 0.74 | KMT2A (0.43) | PPARGLMNANFE2L2ALDH1A1MAPT | |
| SCHEMBL7988652 | 0.74 | PPARG (0.44) | MAOBPPARGLMNAMAPTPOLB | |
| SCHEMBL8004163 | 0.73 | TSHR (0.42) | PPARGLMNANFE2L2ALDH1A1MAPT | |
| Benzene SCHEMBL28814402 | 0.72 | CYP19A1 (0.71) | CYP19A1MAOAMAOBNFE2L2ALDH1A1 | |
| SCHEMBL27279153 | 0.72 | CYP19A1 (0.71) | CYP19A1MAOAMAOBNFE2L2ALDH1A1 | |
| SCHEMBL7997495 | 0.72 | PTGES2 (0.44) | PPARGLMNANFE2L2ALDH1A1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120783-A1 | HIGH AFFINITY INHIBITORS OF HEPATITIS C VIRUS NS3/4A PROTEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-10-01 | — | — | WO | disclosed |