Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ENTPD5 | O75356 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405048 | 0.88 | LMNA (0.38) | LMNAALDH1A1CYP3A4ALOX12PDK2 | |
| SCHEMBL8403336 | 0.83 | ALDH1A1 (0.37) | LMNAALDH1A1CYP3A4OPRD1FTO | |
| SCHEMBL29459356 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL728580 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL7996227 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL7996188 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL18415542 | 0.78 | MAPT (0.39) | LMNAALDH1A1CYP3A4MAPTALOX12 | |
| SCHEMBL7773878 | 0.77 | LMNA (0.35) | LMNAALDH1A1CYP3A4ALOX12PDK2 | |
| SCHEMBL7577079 | 0.77 | OPRD1 (0.43) | LMNAALDH1A1CYP3A4OPRD1ACHE | |
| SCHEMBL9721391 | 0.77 | OPRM1 (0.41) | LMNAALDH1A1CYP3A4MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288204-B1 | CONDENSATION POLYMERIZATION OF BISPHENOL A, TRIHYDRIC PHENOL, AND PHOSGENE; ADDING TETRAAMMONIUM SALT AND MONOHYDRIC PHENOL FOR MOLECULAR WEIGHT CONTROL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2001-09-11 | — | — | US | disclosed |