Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434856 | 0.83 | ADORA3 (0.50) | KDM4ECYP3A4MAPTADORA3ADORA2A | |
| SCHEMBL7295129 | 0.81 | MAPK14 (0.51) | KDM4ECYP3A4MAPTCCNB2CDK1 | |
| Lofemizole SCHEMBL35441 | 0.79 | ADORA3 (0.47) | KDM4ECYP3A4MAPTADORA3ADORA2A | |
| SCHEMBL21428970 | 0.79 | MAPK14 (0.54) | KDM4ECYP3A4MAPTSMN1; SMN2MAPK14 | |
| SCHEMBL3141937 | 0.79 | ASIC3 (0.41) | KDM4ECYP3A4MAPTADORA3ADORA1 | |
| SCHEMBL2691682 | 0.79 | CYP2A6 (0.56) | KDM4ECYP3A4MAPTIDO1HPGD | |
| Lofemizole SCHEMBL44549 | 0.78 | SMN1; SMN2 (0.47) | KDM4ECYP3A4MAPTADORA3ADORA2A | |
| SCHEMBL224770 | 0.76 | KDM4E (1.00) | KDM4ECYP3A4MAPTADORA3ADORA2A | |
| SCHEMBL21400340 | 0.74 | KDM4E (0.67) | KDM4ECYP3A4MAPTADORA3ADORA2A | |
| SCHEMBL544140 | 0.74 | KDM4E (0.61) | KDM4ECYP3A4MAPTADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490668-A | Pyrimidyl imidazole compound, preparation method thereof and organic weldable protective agent | 深圳市贝加电子材料有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-100572362-C | A kind of diphenyl-imidazole compound and preparation method thereof | DONGSHUO SCIENCE AND TECHNOLOG (CN) | 2009-12-23 | — | — | CN | claimed |
| CN-1944414-A | Diphenyl-imidazole compound and its preparing method | DONGHUO SCIENCE AND TECHNOLOGY (CN) | 2007-04-11 | — | — | CN | claimed |
| US-20250215572-A1 | SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY | SHIKOKU CHEMICALS CORPORATION (JP) | 2025-07-03 | — | — | US | disclosed |
| EP-4506488-A1 | SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY | Shikoku Chemicals Corporation (JP) | 2025-02-12 | — | — | EP | disclosed |
| CN-115490668-B | Pyrimidylimidazole compound, preparation method thereof and organic solderability preservative | 深圳市贝加电子材料有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023190263-A1 | SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY | 四国化成工業株式会社 | 2023-10-05 | — | — | WO | disclosed |
| CN-115490668-A | Pyrimidyl imidazole compound, preparation method thereof and organic weldable protective agent | 深圳市贝加电子材料有限公司 | 2022-12-20 | — | — | CN | disclosed |
| EP-3559009-B1 | COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY | CALITHERA BIOSCIENCES INC (US) | 2021-04-07 | — | — | EP | disclosed |
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |
| EP-3725785-A1 | GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2020-10-21 | — | — | EP | disclosed |
| US-20110046066-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| CN-100572362-C | A kind of diphenyl-imidazole compound and preparation method thereof | DONGSHUO SCIENCE AND TECHNOLOG (CN) | 2009-12-23 | — | — | CN | disclosed |
| CN-100572362-C | A kind of diphenyl-imidazole compound and preparation method thereof | DONGSHUO SCIENCE AND TECHNOLOG (CN) | 2009-12-23 | — | — | CN | disclosed |
| CN-1944414-A | Diphenyl-imidazole compound and its preparing method | DONGHUO SCIENCE AND TECHNOLOGY (CN) | 2007-04-11 | — | — | CN | disclosed |
| US-7202381-B2 | Compounds as opioid receptor modulators | JANSSEN PHARMACEUTICA, NV (BE) | 2007-04-10 | — | — | US | disclosed |
| WO-2006114371-A1 | NOVEL COMPOUNDS FOR TREATING INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-02 | — | — | WO | disclosed |
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |
| WO-1999051590-A1 | SUBSTITUTED INDOLINONES AS KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-14 | — | — | WO | disclosed |
| CN-1060466-A | Derivatives of Benzene, Pyridine and Pyrimidine | EISAI CO LTD (JP) | 1992-04-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046066-A1 | INHIBITORS OF IAP | BIRC5, XIAP, BIRC3 | KDM4E 2867/4885CYP3A4 4832/4885MAPT 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.