Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraethylene Glycol SCHEMBL14109914 | 1.00 | MEN1 (0.79) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL4067863 | 0.96 | TSHR (0.77) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL7858578 | 0.94 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL10423729 | 0.93 | MEN1 (0.79) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL8014385 | 0.91 | ALDH1A1 (0.82) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL1123497 | 0.91 | ALDH1A1 (0.82) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL1925152 | 0.91 | ALDH1A1 (0.72) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL20266549 | 0.90 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL9839242 | 0.90 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL3918883 | 0.90 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2825286-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | ExxonMobil Research and Engineering Company (US) | 2015-01-21 | — | — | EP | claimed |
| US-20130243676-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-09-19 | — | — | US | claimed |
| WO-2013138443-A1 | AMINE TREATING PROCESS FOR ACID GAS SEPARATION USING BLENDS OF AMINES AND ALKYLOXYAMINES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-09-19 | — | — | WO | claimed |
| US-11981768-B2 | Polyol component and use thereof for producing rigid polyurethane foams | BASF SE (DE) | 2024-05-14 | — | — | US | disclosed |
| EP-3941955-B1 | POLYOL COMPONENT AND USE THEREOF FOR PRODUCING RIGID POLYURETHANE FOAMS | BASF SE (DE) | 2023-12-13 | — | — | EP | disclosed |
| US-11369919-B2 | Absorbent for selective removal of hydrogen sulfide from a fluid stream | BASF SE (DE) | 2022-06-28 | — | — | US | disclosed |
| US-20220162372-A1 | Polyol component and use thereof for producing rigid polyurethane foams | BASF SE (DE) | 2022-05-26 | — | — | US | disclosed |
| US-11286329-B2 | Polyol component and use thereof for the production of rigid polyurethane foams | BASF SE (DE) | 2022-03-29 | — | — | US | disclosed |
| US-11278841-B2 | Removal of hydrogen sulphide and carbon dioxide from a stream of fluid | BASF SE (DE) | 2022-03-22 | — | — | US | disclosed |
| EP-3941955-A1 | POLYOL COMPONENT AND USE THEREOF FOR PRODUCING RIGID POLYURETHANE FOAMS | BASF SE (DE) | 2022-01-26 | — | — | EP | disclosed |
| US-20210309790-A1 | Polyol component and use thereof for the production of rigid polyurethane foams | BASF SE (DE) | 2021-10-07 | — | — | US | disclosed |
| CN-101313032-B | Light-blocking resin composition, color filter and liquid crystal display device | MITSUBISHI CHEM CORP | 2011-04-06 | — | — | CN | disclosed |
| CN-101326454-B | Method for manufacturing polarizing plate, polarizing plate and liquid crystal display device | KONICA MINOLTA OPTO INC | 2010-11-03 | — | — | CN | disclosed |
| CN-101326454-A | Method for manufacturing polarizing plate, polarizing plate and liquid crystal display device | KONICA MINOLTA OPTO INC (JP) | 2008-12-17 | — | — | CN | disclosed |
| CN-101313032-A | Light-blocking resin composition, color filter and liquid crystal display device | MITSUBISHI CHEM CORP (JP) | 2008-11-26 | — | — | CN | disclosed |
| US-6150452-A | PAPERMAKING | BETZDEARBORN INC. (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0986670-A4 | METHODS AND COMPOSITIONS FOR TREATING STICKIES | BETZDEARBORN INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0986670-A1 | METHODS AND COMPOSITIONS FOR TREATING STICKIES | BetzDearborn Inc (US) | 2000-03-22 | — | — | EP | disclosed |
| US-5936024-A | TREATING THE PAPERMAKING FIBER WITH AN OIL-SOLUBLE OR WATER-DISPERSIBLE MIXTURE OF AT LEAST TWO OF HYDROPHOBIC POLYMER, A SURFACTANT HAVING AN HLB OF ABOUT 1 TO ABOUT 10, A TACKIFIER AND ASOLVENT; MECHANICALLY SEPARATING | BETZDEARBORN INC. (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1998055692-A1 | METHODS AND COMPOSITIONS FOR TREATING STICKIES | BETZDEARBORN INC. (US) | 1998-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11278841-B2 | Removal of hydrogen sulphide and carbon dioxide from a stream of fluid | C1R, MSRB3, HRH4 | MEN1 3400/4885KMT2A 3438/4885TSHR 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.